The Women of Oregon also earned a combined team award for their work in the classroom.
The three-day meet begins Friday with Cravon Gillespie and Tristan James in the 100 and long jump, respectively.
There are 11 former UO standouts entered including Cravon Gillespie and Jessica Hull in their professional debuts.
Edwards' 13.21 also ties the No. 3 junior (39 cm) performance in American history.
The opening round of the 110-meter hurdles is scheduled for Saturday at 12:18 p.m. (PT).
This is the Ducks' 10th team award in the award's 11-year existence.