California men's water polo and UCLA women's soccer won a national championship in their respective sports in 2022, bringing the Pac-12’s all-time title count to 546 to conclude the year. The Golden Bears erased a four-goal deficit to secure back-to-back NCAA titles, while the Bruins earned the second national championship in program history. UCLA head coach Margueritte Aozasa became the first first-year head coach to lead her team to a women’s soccer national title.